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Nitrogenous bases covalently linked to a sugar with and without phosphate groups; used for synthesis, cell signaling, and as cofactors in enzymatic reactions; includes pyrimidine, purine, pyridine, flavin, pyrrolopyrimidine, and triazole varieties.
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Adenosine antagonist-1 is a research-grade small molecule that acts as a selective adenosine A3 receptor (A3R) antagonist with reported anti-inflammatory activity. It is provided in solid and solution formats with analytical characterization suitable for in vitro pharmacology and receptor signaling studies.
Adenosine A3 receptor (A3R) antagonist.
Demonstrated anti-inflammatory activity.
High purity suitable for research applications (99.79%).
Molecular formula C18H13N7S and molecular weight 359.41 g/mol.
Available as solid and DMSO solution formats for flexible dosing.
Supplied for research use only; not for human use.
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Adenosine N1-oxide is a nucleoside derivative used in research as an orally active anti-inflammatory agent. It has been reported to promote osteogenic and adipocyte differentiation and is supplied as a purified research-grade solid with supporting documentation (COA, SDS).
CAS 146-92-9
Molecular formula C10H13N5O5
Molecular weight 283.24 g/mol
Purity 99.50%
Available in small vial sizes for research use (e.g., 1-25 mg)
Documentation: certificate of analysis and safety data sheet available
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L-adenosine is an enantiomeric analog of adenosine used as a research reagent and a weak adenosine deaminase (ADA) inhibitor (reported Ki = 385 μM). It is supplied as a high-purity solid for studies of adenosine uptake, accumulation, and ADA-related metabolism.
High purity - 99.82% (reported).
Suitable for adenosine uptake and accumulation studies.
Weak ADA inhibitor (Ki ≈ 385 μM).
Available as a 50 MG solid; additional pack sizes and DMSO solutions are offered.
Molecular weight 267.24 g/mol; formula C10H13N5O4.
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Adenosine 5-triphosphate (ATP CAS 34369-07-8) also known as ATP disodium salt hydrate is a nucleotide central to cellular energy transfer It functions as the primary intracellular energy carrier undergoing hydrolysis to release energy required for numerous biochemical processes including muscle contraction signal transduction and biosynthetic reactions ATP also serves as a substrate for kinases in phosphorylation events and plays a regulatory role in purinergic signaling pathways In biomedical research ATP is widely used to study cellular metabolism enzyme activities and receptor-mediated responses
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This compound is a potent adenosine receptor (AR) inhibitor, demonstrating dual affinity for A1 and A2A ARs. It exhibits higher affinity for the A1AR compared to the A2AAR.
Potent AR inhibitor
Dual affinity for A1 and A2A ARs
Ki values: 52.2 nM for A1AR and 167 nM for A2AAR
For research use only
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Kinetin triphosphate tetrasodium is an ATP analogue used in biochemical and kinase research, including investigations of mitochondrial quality control pathways. It is supplied as a tetrasodium salt in small milligram quantities and includes documentation for experimental use and handling.
ATP analogue for kinase and enzymology assays.
High purity (99.92%) suitable for sensitive biochemical studies.
Soluble in water with recommended reconstitution guidance (100 mM preparations).
Provided in small research quantities for experimental flexibility.
Documentation includes datasheet, certificate of analysis, and safety data sheet.
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6-O-Methyl Guanosine is identified as a modified nucleoside. Research indicates its capacity to inhibit the colony-forming ability in a malignant xeroderma pigmentosum cell line, suggesting potential applications in cell biology studies related to cell proliferation and specific genetic disorders. This modified nucleoside provides a tool for investigating cellular mechanisms and could contribute to understanding pathways involved in malignancy.
Modified nucleoside.
Inhibits colony-forming ability in a malignant xeroderma pigmentosum cell line.
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ATP-Red 1 is a multisite-binding switchable fluorescent probe that selectively and rapidly responds to intracellular concentrations of ATP in living cells.
Multisite-binding switchable fluorescent probe
Selectively and rapidly responds to intracellular concentrations of ATP in living cells
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Guanosine 5'-diphosphate (GDP) sodium, 96% (HPLC), is a nucleoside diphosphate that activates the adenosine 5'-triphosphate-sensitive K+ channel. It functions as an iron mobilizer by forming a complex with hepcidin, thereby inhibiting the hepcidin-ferroportin (FPN) interaction and modulating the IL-6/stat-3 pathway. This compound can ameliorate Turpentine-induced anemia of inflammation (AI) in mice when combined with FeSO4 and is suitable for AI research.